Skip to main content

Table 3 Fixed effects estimates summarized by the mean (standard error) from the direct h-lik implementation for the 1%, 10 and 100% dataset with random effects at both the IP and HCF levels

From: High performance implementation of the hierarchical likelihood for generalized linear mixed models: an application to estimate the potassium reference range in massive electronic health records datasets

Parameter

1%

10%

100%

Fixed Effects

 Intercept

−6.22 (0.99)

−5.22 (0.31)

−3.21 (0.16)

 Potassium (natural spline coefficient 1)

6.81 (2.46)

8.65 (0.74)

11.98 (0.32)

 Potassium (natural spline coefficient 2)

−9.49 (40.24)

−39.56 (12.39)

−77.79 (7.97)

 Potassium (natural spline coefficient 3)

−18.5 (79.78)

−74.64 (24.57)

− 146.92 (15.84)

 eGFR (natural spline coefficient 1)

−0.43 (0.25)

− 0.66 (0.08)

− 0.59 (0.02)

 eGFR (natural spline coefficient 2)

−1.84 (0.51)

− 1.41 (0.15)

− 1.44 (0.05)

 eGFR (natural spline coefficient 3)

− 1.09 (0.51)

− 0.32 (0.15)

− 0.26 (0.05)

 Age (natural spline coefficient 1)

0.31 (0.33)

0.6 (0.12)

0.78 (0.04)

 Age (natural spline coefficient 2)

−0.23 (0.91)

1.43 (0.32)

2.08 (0.11)

 Age (natural spline coefficient 3)

0.91 (0.2)

1.1 (0.07)

1.22 (0.02)

 Male Gender

0.21 (0.09)

0.17 (0.03)

0.17 (0.01)

 White Race

0.16 (0.15)

0.06 (0.05)

0.1 (0.02)

 Hispanic Race

−0.46 (0.72)

0.14 (0.15)

0.16 (0.05)

 Native American

0.03 (0.73)

−0.08 (0.2)

0.16 (0.06)

 Other Race

−0.58 (0.32)

−0.12 (0.09)

0.08 (0.03)

 Unknown Race

−0.24 (0.47)

−0.09 (0.15)

0.02 (0.05)

 Inpatient status

2.39 (0.19)

2.13 (0.06)

2.21 (0.02)

 Charlson Comorbidity Score

0.10 (0.01)

0.10 (0.00)

0.10 (0.00)