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Table 1 Start and end of analysis window within observation period for continuous, multiple interval, measures of medication availability

From: Estimating medication adherence from Electronic Health Records: comparing methods for mining and processing asthma treatment prescriptions

Adherence Measure

Start of Window

End of Window

Derivation

CMA1

Day of first prescription

Day before final prescription

\(\frac{\mathrm{Supply days obtained in window}}{\mathrm{Window duration}}\)

CMA2

Day of first prescription

End of observation period

\(\frac{\mathrm{Supply days obtained in window}}{\mathrm{Window duration}}\)

CMA3

Day of first prescription

Day before final prescription

minimum (CMA1, 1)

CMA4

Day of first prescription

End of observation period

minimum (CMA2, 1)

CMA5

Day of first prescription

Day before final prescription

\(\frac{\mathrm{Days with medication available in window}}{\mathrm{Window duration}}\)

CMA6

Day of first prescription

End of observation period

\(\frac{\mathrm{Days with medication available in window}}{\mathrm{Window duration}}\)

CMA7

Start of observation period

End of observation period

\(\frac{{\mathrm{Days with medication available }}^{a}\mathrm{ in window}}{\mathrm{Window duration}}\)

CMA8

Day that supply that was available at the start of observation period theoretically exhausted

End of observation period

\(\frac{{\mathrm{Days with medication available }}^{b}\mathrm{ in window}}{\mathrm{Window duration}}\)

  1. aaccounting for supply remaining, at the start of observation from dispensings prior to observation
  2. baccounting for supply obtained between the start of observation and the start of the window