Table 1 Baseline characteristics for the CATIE and each of the RCTs. Proportions are presented for categorical variables and means and standard deviations in parenthesis are presented for continuous variables
| Â | Target Population | Randomized Controlled Trials | |||
|---|---|---|---|---|---|
| Â | CATIE | NCT00074477 | NCT00210548 | NCT00101634 | NCT00590577 |
N | 1458 | 243 | 349 | 511 | 635 |
Female (%) | 26.1 | 32.9 | 30.7 | 33.7 | 32.8 |
Race (%) | |||||
 White | 59.9 | 71.2 | 40.4 | 66.9 | 53.9 |
 African-American | 35.1 | 16.5 | 38.7 | 28.6 | 30.2 |
 Other | 5.0 | 12.3 | 20.9 | 4.5 | 15.9 |
Age, year (%) | |||||
  ≤ 30 | 21.3 | 26.3 | 21.8 | 21.7 | 24.7 |
 30–40 | 24.0 | 28.8 | 30.1 | 24.9 | 28.2 |
 40–50 | 35.3 | 32.9 | 30.4 | 32.9 | 32.4 |
  > 50 | 19.4 | 11.9 | 17.8 | 20.5 | 14.6 |
Onset age, year (%) | |||||
  ≤ 20 | 30.2 | 31.7 | 35.1 | 31.6 | 32.9 |
 20–30 | 46.2 | 41.2 | 43.1 | 40.7 | 43.1 |
 30–40 | 16.1 | 20.4 | 16.1 | 18.1 | 19.4 |
 > 40 | 7.5 | 6.7 | 5.7 | 9.6 | 4.6 |
Weight, kg (%) | |||||
  ≤ 70 | 18.3 | 46.3 | 32.1 | 35.0 | 35.3 |
 70–80 | 20.9 | 19.0 | 17.8 | 22.5 | 26.5 |
 80–90 | 18.5 | 18.6 | 15.8 | 15.9 | 14.0 |
 90–100 | 16.0 | 10.7 | 13.2 | 9.4 | 13.1 |
 100–110 | 12.5 | 3.3 | 7.7 | 7.0 | 3.6 |
  > 110 | 13.7 | 2.1 | 13.5 | 10.2 | 7.6 |
PANSS (mean [SD], [min, max]) | 75.65 (17.57) [31, 140] | 87.86 (12.20) [55, 120] | 91.09 (11.80) [70, 120] | 90.85 (12.03) [70, 120] | 87.07 (11.20) [61, 131] |