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Table 6 Upper 95% confidence limits for \(\frac{{\theta_{E} - \theta_{P} }}{{\theta_{R} - \theta_{P} }}\), based on the positive control of 25 mg/kg cyclophosphamide

From: Conducting the non-inferiority test for the means with unknown coefficient of variation in a three-arm trial

Treatment group

P-value

Upper confidence limit

GPV-based method

Delta method

Empirical bootstrap method

30 mg/kg

0.0018

0.28

0.13

0.08

50 mg/kg

0.0044

0.41

0.29

0.23

75 mg/kg

0.2474

0.97

0.74

0.74

100 mg/kg

0.8566

1.39

1.06

1.13

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BMC Medical Research Methodology

ISSN: 1471-2288

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