From: Predicting lung cancer survival prognosis based on the conditional survival bayesian network
 | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
Characteristic | Beta | HR (95% CI) | P | Beta | HR (95% CI) | P |
Gender | ||||||
 Female | Reference | Reference | ||||
 Male | 0.799 | 2.224 (1.864–2.654) | <0.001 | 0.074 | 1.077 (0.839–1.383) | 0.560 |
Age | ||||||
  (18,44] | Reference | Reference | ||||
  (44,59] | 0.784 | 2.190 (1.117–4.296) | 0.023 | −0.037 | 0.964 (0.487–1.909) | 0.916 |
  (59,74] | 1.107 | 3.025 (1.560–5.865) | 0.001 | 0.108 | 1.114 (0.567–2.191) | 0.754 |
  (74,92] | 1.758 | 5.800 (2.897–11.612) | <0.001 | 0.509 | 1.664 (0.822–3.372) | 0.157 |
Smoking | ||||||
 Never | Reference | Reference | ||||
 Current | 1.033 | 2.809 (2.321–3.398) | <0.001 | 0.585 | 1.795 (1.306–2.466) | <0.001 |
 Former | 0.628 | 1.874 (1.497–2.345) | <0.001 | 0.186 | 1.205 (0.881–1.647) | 0.243 |
Drinking | ||||||
 no | Reference | Reference | ||||
 yes | 0.686 | 1.986 (1.672–2.359) | <0.001 | −0.172 | 0.842 (0.650–1.092) | 0.195 |
NSCLC | ||||||
 no | Reference | Reference | ||||
 yes | −1.117 | 0.327 (0.265–0.404) | <0.001 | −0.09 | 0.914 (0.736–1.135) | 0.416 |
Radiotherapy | 0.431 | 1.539 (1.290–1.836) | <0.001 |  |  |  |
Chemotherapy | 0.555 | 1.743 (1.475–2.060) | <0.001 |  |  |  |
Targeted therapy | 0.656 | 1.928 (1.627–2.284) | <0.001 | −0.459 | 0.632 (0.525–0.761) | <0.001 |
COPD | 0.633 | 1.884 (1.591–2.230) | <0.001 | 0.195 | 1.216 (1.009–1.465) | 0.040 |
Pneumonia | 0.93 | 2.535 (2.145–2.996) | <0.001 | 0.125 | 1.133 (0.946–1.359) | 0.176 |
Pleural effusion | 1.063 | 2.894 (2.431–3.445) | <0.001 |  |  |  |
STAGE | ||||||
 I | Reference | Reference | ||||
 II | 1.888 | 6.607 (3.105–14.058) | <0.001 | 1.778 | 5.916 (2.771–12.631) | <0.001 |
 III | 3.234 | 25.393 (14.608–44.140) | <0.001 | 3.027 | 20.644 (11.716–36.377) | <0.001 |
 IV | 3.897 | 49.263 (28.908–83.952) | <0.001 | 3.716 | 41.091 (23.662–71.356) | <0.001 |
URI | −0.445 | 0.641 (0.443–0.926) | 0.018 |  |  |  |
Lung abscess | 0.876 | 2.402 (1.322–4.365) | 0.004 |  |  |  |
Pulmonary embolism | 1.138 | 3.121 (2.037–4.783) | <0.001 |  |  |  |
Pulmonary heart disease | 1.013 | 2.753 (1.954–3.877) | <0.001 |  |  |  |
ILD | 1.022 | 2.779 (1.980–3.899) | <0.001 | 0.416 | 1.515 (1.063–2.159) | 0.021 |
Respiratory failure | 1.368 | 3.926 (2.902–5.313) | <0.001 | 0.628 | 1.873 (1.362–2.577) | <0.001 |
Red blood cell count | ||||||
 T1 | Reference |  | ||||
 T2 | 0.517 | 1.678 (1.300–2.166) | <0.001 |  |  |  |
 T3 | 1.039 | 2.825 (2.219–3.598) | <0.001 |  |  |  |
Eosinophil | ||||||
 T1 | Reference |  | ||||
 T2 | 0.517 | 1.678 (1.300–2.166) | <0.001 |  |  |  |
 T3 | 1.039 | 2.825 (2.219–3.598) | <0.001 |  |  |  |
Fibrinogen | ||||||
 T1 | Reference | Reference | ||||
 T2 | 0.804 | 2.234 (1.711–2.917) | <0.001 | 0.276 | 1.318 (1.004–1.730) | 0.047 |
 T3 | 1.754 | 5.780 (4.537–7.363) | <0.001 | 0.57 | 1.769 (1.374–2.277) | <0.001 |
Direct bilirubin | ||||||
 T1 | Reference |  | ||||
 T2 | −0.396 | 0.673 (0.556–0.816) | <0.001 |  |  |  |
 T3 | −0.774 | 0.461 (0.370–0.575) | <0.001 |  |  |  |