Table 1 Clinicopathologic features of the breast cancer patients (n =1901)
Characteristics | Whole cohort | Alive | Died of breast cancer | P value |
|---|---|---|---|---|
N = 1901 (%) | N = 1828 (%) | N = 73 (%) | ||
Age | 0.290 | |||
≤70 | 1440 (75.7) | 1389 (76.0) | 51 (69.9) | |
>70 | 461 (24.3) | 439 (24.0) | 22 (30.1) | |
Race | 0.206 | |||
White people | 1484 (78.1) | 1433 (78.4) | 51 (69.9) | |
Black people | 224 (11.8) | 213 (11.7) | 11 (15.1) | |
Other people | 193 (10.2) | 182 (10.0) | 11 (15.1) | |
Marital status | 0.003 | |||
Unmarried | 792 (41.7) | 749 (41.0) | 43 (58.9) | |
Married | 1109 (58.3) | 1079 (59.0) | 30 (41.1) | |
Tumor size | <0.001 | |||
≤20 mm | 1137 (59.8) | 1115 (61.0) | 22 (30.1) | |
21-50 mm | 589 (31.0) | 556 (30.4) | 33 (45.2) | |
>50 mm | 175 (9.2) | 157 (8.6) | 18 (24.7) | |
N status | <0.001 | |||
N0 | 1053 (55.4) | 1030 (56.3) | 23 (31.5) | |
N1 | 547 (28.8) | 529 (28.9) | 18 (24.7) | |
N2 | 187 (9.8) | 174 (9.5) | 13 (17.8) | |
N3 | 114 (6.0) | 95 (5.2) | 19 (26.0) | |
eLN, mean (SD) | 6.6 (7.2) | 6.4 (7.1) | 10.6 (8.1) | <0.001 |
pLN, mean (SD) | 1.9 (4.0) | 1.8 (3.7) | 5.6 (7.2) | <0.001 |
TNM staging (AJCC-8th) | <0.001 | |||
I | 819 (43.1) | 804 (44.0) | 15 (20.5) | |
II | 733 (38.6) | 707 (38.7) | 26 (35.6) | |
III | 349 (18.4) | 317 (17.3) | 32 (43.8) | |
Histological grade | <0.001 | |||
I-II | 1239 (65.2) | 1217 (66.6) | 22 (30.1) | |
III-IV | 662 (34.8) | 611 (33.4) | 51 (69.9) | |
Estrogen receptor status | <0.001 | |||
Negative | 146 (7.7) | 125 (6.8) | 21 (28.8) | |
Positive | 1755 (92.3) | 1703 (93.2) | 52 (71.2) | |
Progesterone receptor status | <0.001 | |||
Negative | 317 (16.7) | 283 (15.5) | 34 (46.6) | |
Positive | 1584 (83.3) | 1545 (84.5) | 39 (53.4) | |
Her-2 status | 0.290 | |||
Negative | 1508 (79.3) | 1446 (79.1) | 62 (84.9) | |
Positive | 393 (20.7) | 382 (20.9) | 11 (15.1) | |
Molecular subtypes | <0.001 | |||
Luminal A | 1444 (76.0) | 1397 (76.4) | 47 (64.4) | |
Luminal B | 319 (16.8) | 312 (17.1) | 7 (9.6) | |
Her-2 overexpression | 74 (3.9) | 70 (3.8) | 4 (5.5) | |
Triple negative | 64 (3.4) | 49 (2.7) | 15 (20.5) | |
Surgery | <0.001 | |||
Breast conserving surgery | 1078 (56.7) | 1052 (57.5) | 26 (35.6) | |
Mastectomy | 823 (43.3) | 776 (42.5) | 47 (64.4) | |
Radiotherapy | 0.389 | |||
No\Unknown | 780 (41.0) | 746 (40.8) | 34 (46.6) | |
Yes | 1121 (59.0) | 1082 (59.2) | 39 (53.4) | |
Chemotherapy | 0.028 | |||
No\Unknown | 981 (51.6) | 953 (52.1) | 28 (38.4) | |
Yes | 920 (48.4) | 875 (47.9) | 45 (61.6) |